Treatment of gout with uricosuric drugs can lead to uric acid nephrolithiasis.
2.
Guaifenesin is mildly uricosuric but, unlike standard uricosuric drugs, has almost no side-effects.
3.
The treatment was discovered serendipitously when the physician found that uricosuric drugs for treating gout also coincided with relief of fibromyalgia symptoms.
4.
In borderline cases, enough water to produce 2 liters of urine per day may be sufficient to permit use of an uricosuric drug.
5.
While this is occasionally exploitable to good effect ( see oseltamivir ), assessment of drug interactions is very important when using uricosuric drugs in the presence of other medications.
6.
Benzbromarone is highly effective and well tolerated, and clinical trials as early as 1981 and as recently as April 2008 have suggested it is superior to both allopurinol, a xanthine oxidase inhibitor but not uricosuric, and probenecid, another uricosuric drug.
मोबाइल